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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

[di'sin]
《华胥引》

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Around 280 million train tickets have been sold on 12306.cn since Jan 3, 2018 when tickets for the Spring Festival holiday started selling.
今年世界卫生组织宣布H1N1型流感为全球性传染病。庆幸的是,这种病毒远没有人们最初想的那样危险,而最新面世的疫苗似乎已经平息了那弥留在人们心头久久不能散去的恐惧。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

But, despite the incessant warnings from security researchers, many people are still turning to weak, easily guessable passwords to protect their devices.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

愿你度过最美好的新年!

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Aaron Hernandez
李亦表示:“贫困阻碍了网民数量的进一步增加,使得网民数量占全部人口的比例只在50%左右。”
Chinese consumer prices rose in January, an encouraging sign for the world’s second largest economy in a month characterised by turbulence in its financial markets.
年度最佳合唱:埃里克·丘奇、杰森·阿尔丁、卢克布·莱恩《The Only Way I Know》

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

挪威诺贝尔和平奖委员会表示,希望这次的颁奖有助于制止在很多国家内仍然存在的对女性的压迫。
单词elite 联想记忆:
她也曾应邀参加《吉米秀》(Jimmy Kimmel)和《艾伦秀》(The Ellen Show)。对于一个青春期未到的人来说,有机会上这两个节目还算不错。
如果你处于失业状态:

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 广州81个房地产项目违规被查
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

n. 理解力,智力

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Four other domestic movies made it to the top ten list, among them are the third winner Never Say Die, Kung Fu Yoga in the fourth place, the fifth winner Journey to the West: The Demons Strike Back, and Youth in the eighth place.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

尽管在奥巴马担任美国总统的过去的四年里,美国经济复苏缓慢、失业率居高不下,奥巴马在几个关键的摇摆州获得的选票还是高于罗姆尼。美国选民在两种风格明显迥异的国家发展愿景中做出了自己的决定。
凯文·杜兰特

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

我其实好奇鹈鹕队会不会也会到这一地步。目测布朗时代最高顺位的新秀就是巴迪-希尔德了,这可不理想。
与此同时,最近几个月,中国内地投资者一直在迅速开设股票交易账户并将资金投入股市。上证综指已成为亚洲今年表现最佳的股指,今年迄今已累计上涨近45%。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

A. O. Scott
n. 非法移民

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

吉迪恩拉赫曼(Gideon Rachman)
In eighth place with $6.5 million, Chinese model Liu Wen, 29, is the only Asian model on the list, reflecting the lack of diversity that continues to plague runways.
She’s No. 1: Chancellor Merkel has made the list eight times out of the past ten years — seven times as No. 1.
According to the index, tourists are "spending overwhelmingly" to shop -- and not to dine -- in the top 20 destinations outside of Europe, despite many of them being world-famous cuisine capitals.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

没有什么比老板所说和所做不一样更糟糕了,也没有什么比守信用更重要了。就像经理们一定要相信他们的团队,员工一定要相信他们的老板心中会为他们带来最佳利益。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

北韩已经警告过Park,如果电影穿越边境,将会要他"以命偿罪"。
中国一群现代汽车经销商要求韩国现代汽车赔偿8-9亿元(1.2-1.35亿美元),称现代汽车削减了向他们出口的车型,导致经销商亏损严重。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

5. Geopolitical flashpoints.In the not too distant past, a small supply disruption would send oil prices skyward. In early 2014, for example, violence in Libya blocked oil exports, contributing to a rise in oil prices. In Iraq, ISIS overran parts of the country and oil prices shot up on fears of supply outages. But since then, geopolitical flashpoints have had much less of an effect on the price of crude. During the last few weeks of 2014, violence flared up again in Libya. But after a brief increase in prices, the markets shrugged off the event. Nevertheless, history has demonstrated time and again that geopolitical crises are some of the most powerful short-term movers of oil prices.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 贝壳盖的房子见证海上丝绸之路
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

我敢保证,魔兽霍华德从未用过生长激素,但在其他人看来,他似乎用了很多。自从离开高中进入NBA后,霍华德的体形似乎翻了一番。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

SETTING: This house is in Kenwood, a neighborhood of 19th- and 20th-century Tudors, Mediterraneans, Victorians and colonial-style houses between Cedar Lake and Lake of the Isles, in the city’s Chain of Lakes. Roads are curving; sidewalks are lined with maple and ash trees. According to the listing agent, many of the neighborhood’s older houses have been restored, while houses built within the last 30 years have been torn down and replaced.
Analysts say headline import figures may start to improve in the coming months since commodity price falls were particularly pronounced at the end of 2014, which will mean smaller year-on-year falls in Chinese imports in value terms.
Build the armed forces through political work and reform, and run them by law
Better still was Iain Roberts, global managing director of the design company Ideo, who asked a question to which I hope never to hear the answer: “How to activate insights around latent mobility or multimodal needs?”

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

罗杰斯夫人还表示,正如条款中所述,她并没有同意她的儿子玩这个游戏。此外,由于这个游戏是免费的,所以该工作室不能够断言因为作弊软件而造成了利润损失。
我发现自己很难开启一段对话
这个价码看起来很合适,因为塔克应该比罗斯更适应3D角色,而萨林杰完全无关紧要,同时猛龙保留了他们自己的2017年一轮选秀权
200910/87441.shtml
Stevens will perform "Mystery of Love" from the film "Call Me by Your Name," and Bernal, LaFourcade and Miguel will perform "Remember Me" from "Coco."

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

“With the vast number of cutting-edge, eco-friendly faux furs available on the market today, I'm sure you'll agree that there's no longer any excuse for killing animals for their fur.”
Intel

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

沃尔玛百货

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Beauty and Evolution

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

珍妮·德文表示,“这并不是借口——这是我们经营环境的现实情况。”2012年以来,捷蓝航空公司实施了一系列技术手段,帮助该公司尽快恢复正常,摆脱恶劣天气的影响。她表示,正在使用其他手段来帮助航空公司保证航班准时起降。
element
下面是2014年的几部重现活力、需要刮目相看的老剧——以及几部死气沉沉的老剧。
单词population 联想记忆:

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

要实现有效的电子邮件营销,可不只是偶尔发一封电子文宣邮件那么简单。要想构建一套有效的电子邮件营销战略,你需要一个功能齐全的工具。MailChimp似乎是市面上最佳的此类系统,它提供了各种典雅直观的电邮广告模板、先进的分段功能和营销自动化功能。
Matthew McConaughey and Jared Leto both won for their startlingly gaunt performances in the Texas HIV drama 'Dallas Buyers Club.' Leonardo DiCaprio, a nine-time Golden Globe nominee, won his second Globe for best actor in a comedy for his uninhibited work in 'The Wolf of Wall Street.' He thanked director Martin Scorsese for his mentorship ('Wolf' is their fifth film together) and for 'allowing me to stalk you to make this movie.'
“An employee baked a cake with her resignation letter written on top.”
9、邦德经历风险无数却总能死里逃生。当然,人物本身是虚构的。有意思的是,研究证明,肌肉男更皮实。实际上,肌肉不发达对男性来说,可能很要命。(可能就是发达的肌肉让他得以活命的吧,我怀疑他会死于心脏病或前列腺癌)。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

What? Hasn't his firm made enough money off Bernanke's cheap money printing? So he's blaming 'lower growth on fiscal austerity, ' even as Bernanke keeps blowing up the Fed's balance-sheet bubble by trillions under the delusion he's America's savior because our dysfunctional Congress failed?
0=false

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

The recovery may help allay some of the gloom around emerging market countries, many of which used strong export growth as a springboard for rapid economic advancement in the early years of this century, before the export boom turned to bust.
US president Donald Trump’s zero-sum, Art-of-the-Deal approach to negotiation will give comfort to old-fashioned incumbents. I am hoping 2018 will provide an opportunity for positive, problem-solving new leaders to emerge. But change could stall if business chiefs, disheartened by the poor quality of political leadership, turn inwards instead.
科技、电信企业与一些快餐集团的品牌价值均出现增长,后者包括星巴克(BrandZ将它列入这一分类)和麦当劳(McDonald's),麦当劳的品牌价值增长9%,尽管排名没有变化。
8. Flats are allowed on the red carpet – or are they?
2016年,中国电影票房经历了一次令人震惊的调整,从2015年的48%大幅下降到3.7%。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

FOYLE’S WAR (acorn.tv, Feb. 2) After nabbing the final three episodes of “Agatha Christie’s Poirot” last year, the streaming service Acorn TV scores another coup in the field of traditional British mysteries with the American premiere of this superior show’s ninth season. Starring Michael Kitchen as Christopher Foyle, a detective as honorable as he is shrewd, the series has morphed over the years from a provincial home-front cop show to a le Carré-like Cold War thriller. New episodes involve the Nuremberg trials and Britain’s role in Palestine.
While a way must be found to aggregate those views, it will always be defective.
The Killing of a Sacred Deer

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 开学季来临 儿童家居市场加温
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

v. 伸展,展开,传播,散布,铺开,涂撒
Will the BoJ tighten monetary policy

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 我国城市化减速了吗?
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

n. 决定,决策
Best Companies rank: 11
南非总统雅各布?祖马的工资于三月份上调4%,但由于南非兰特的贬值,换算成美元后,其收入较去年实际有所下滑。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

pressure
在其他杯赛中,尽管没有做调查,但同样也呈现出类似趋势。
With an increase of 7 percent over 2013,total spending on medicines will amount to $1.06trillion in 2014, says the report"The Global Use of Medicines: Outlook through2018" from the IMS Institute for Healthcare Informatics, releasedThursday.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

It shifts your kid's weight to your shoulders and core instead of your back.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 投资房地产信托不能单纯信抵押物
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

"The average salary level of employees grew by about 6.3 percent year on year in the first three quarters of last year, while China's annual GDP growth stood at 6.7 percent in 2016, both slowing from a year earlier," Jin added.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Dachis says: Adidas added more than 34 million new fans and followers in just 12 months this year. The company put that audience to good use and benefited from high levels of positive discussion all year long.
Season\'s greetings and sincere wishes for a bright and happy New Year!

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Passion, perseverance and a positive attitude tend to set successful entrepreneurs apart. Cultivating these attributes requires an innate skill set and some tips to get started.
New Year should be a time of banked-up fines, the scent of flowers and wine, good talk, good memories and loyalties renewed. But if all else is lacking - love will do.新年是这样美好的时光:炉火熊熊,花儿芬芳,醇酒飘香,殷殷祝福,美好回忆,恩爱日新。即便没有一切,只要有爱便足矣。
中国商务部(Ministry of Commerce)表示,今年1-10月中国对外投资总计863亿美元。
But that idea did not bring Brexit to the UK or Mr Trump to Washington.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

《权力的游戏》
10. China watchers inthe United States will continue to postulate China’s declining growth rate inthe face of evidence that it is stable at over 7%. China will grow fasterin 2014 than in 2013.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Any 'jobs recovery is years away in most cities, ' says USA Today. And in reviewing famed analyst Meredith Whitney's new book, 'The Fate of States, ' she warns that 'excessive pensions crowd out both liberal goals such as education spending and tax cuts that conservatives want.'
曼谷重回首位,而付出代价的是伦敦。伦敦在连续两年占据榜首后,与其亚洲对手城市交换了位置。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

过去二十多年间,我一直在写关于亚洲崛起及其推动力量的文章。东亚各国领导人之间有一个了不起的共识:亚洲需要利用当前的机会之窗,把重点放在经济发展和增长上。战争是发展的最大阻碍。如果亚洲人真的愚蠢,他们或会卷入这样的战争,破坏自己巨大的发展前景。大多数亚洲国家(除了朝鲜)的领导人,都很明白战争的危险。因此,虽然这一地区会出现局势紧张和对抗,但无论在2014年还是2015年都不会爆发战争。随着2015年缓缓展开,我想鼓励所有西方学者根据亚洲本身的情况理解亚洲的根本发展动力,而非将理解建立在西方先入之见的基础上。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

确实有人有近乎完美的记性,可以从过去经历中检索出大量信息。只是,即使很多人认为这样的记忆已经很完美,他们有的时候也不能准确清晰地记起一些特定的细节。虽然真正完美的记忆并不存在,但你还是可以拥有近乎完美的记忆力,超越这些记忆达人,去抵抗岁月给你带来的疾病和健忘。
"Based on experience from previous years, the number of applicants could sharply increase as the application window closes, especially during the last three days of application," an unidentified official with the Ministry of Human Resource and Social Security said on the ministry's website.
在北大和清华大学之后,中国内地入选该榜单前20名的院校还有中国科学技术大学,该校位居第15位;复旦大学排名第16位,上海交通大学排名第18位,而浙江大学排名第19。
你可能觉得夏威夷航空的运营相对容易,因为该公司的航班很少遇到美国大陆那种恶劣的天气条件。夏威夷航空公司在航班准点率排行榜上常年位居前列,在9月份最新公布的榜单上创下最高准点率。夏威夷航空公司最近宣布将把业务拓展到夏威夷岛外,开通从檀香山到北京的直达航班。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

“A worker sent a text to a colleague saying he was quitting and asked her to forward it to management.”
傲人的财务业绩和令人炫目的新科技,或许已足以让这位钢铁般坚定的苹果首席执行官赢得英国《金融时报》2014年年度人物(Person of the Year)的称号。但库克阐述自己价值观的勇气,同样让他与众不同。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
From the themed collection: 板材国标升级任重道远
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

3.人工胰腺
煽动家是民主的软肋。
"Although it may seem counterintuitive, the best way to maximize profits over the long-term is not to make them the primary goal of the business," Mackey said in an interview earlier this year.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

居民消费价格涨幅3%左右;
王春法说,在出版前应加强审查和评估。
comedy

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Jose's mother Inma Quesada told the El Pais daily that her son "wanted to buy instruments" for his band Los Salerosos (loosely translated as "The Salties"), in which he plays the trumpet.
adj. 可用的,可得到的,有用的,有效的

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

当你和他/她在一起的时候,你看不见周围的所有人,你的眼中只有他/她
在科技初创公司大会上(比如去年12月在赫尔辛基举办的Slush),各方都在讨论体验。未来一年可能会看到更广泛地采用虚拟实境(VR,让用户置身于数字化强化的环境中)和强化实境(AR,把数字信息叠加到现实世界中)来创建新的数字企业。
平板电脑的病毒出现。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

市场观察人士被迫接受一季度美国GDP负增长2.9%这一现实。突然间,同波诡云谲的现实相比,所有人的预测似乎都过于乐观,至少是过于平稳。这导致人们纷纷猜测美联储最终退出其债券购买计划的时机。短短几周内,我们从信心满满变成了垂头丧气,同时,伴随着不确定性的再次来袭,资产类别的交替以及市场调整也随之而来。
凯特哈德森接受ELLE专访谈感情

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

中国官方PMI指数从10月份的50.8跌至11月份的50.3,这是3月份以来的最低读数。高于50的读数表示相关产业处于扩张之中。
具有荷兰和美国双重国籍的Frans de Waal和另一位美国科学家Jennifer Pokorny获得这一奖项,他们的研究确认黑猩猩可以通过辨认同类的屁股照片来认出不同的个体。
adj. 犯罪的,刑事的,违法的

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

根据公安部的声明,自2015年9月以来,我国在放宽外国人居留、入境政策方面取得了巨大进步,帮助吸引了更多海外人才、促进了国际交流和经济发展。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

n. 终极,根本,精华
奥巴马赢得了第二场辩论挽回颓势。虽然他也赢得了第三场,外交政策并不是选民关注的主要问题,这不大可能导致较大的选票波动。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

而关于小牛这支球队,问题并不全是司机该怎么让位。在老司机的整个职业生涯中,这一直是一直有实力的球队。德克今年这样支离破碎的赛季实在令人痛苦。或许下个夏天他就会加入科比、KG和大基本功先生的队伍中去。
Here, you may be delegates of your governments, business people, organisers, reporters or poiticians - but really you are mothers and fathers, brothers and sister, aunts and uncles - and all of you are somebody's child. 在这里,您可能是您政府商业人士的代表、组织者、记者或政客。但您们也是父亲和母亲、兄弟和姐妹、阿姨和叔叔,你们都会或多或少的为了下一代而活着。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

提问
俄罗斯把自己看作超级大国 -- 这在国内是毋庸置疑的。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

A devastating financial crisis led business owners and corporate executives to be especially wary about adding staff or investing in new equipment. Some worry about risks from Washington or overseas. Others are seeing consumers maintain their slow-but-steady spending, providing little incentive to deploy their cash stockpiles.
It will be interesting to see which direction they go at the trade deadline. They have a handful of solid players along with Brook Lopez.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

根据《重庆晨报》报道,今年4月24日,这名16岁的周姓同学将农药倒入了教室的饮水机中,显然是在报复扰乱课堂秩序、影响自己学习的同学们。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

9. Occupational therapist
A new paper on the Dutch debacle, coauthored by Peter Koudijs at Stanford Graduate School of Business, turns up modern-day lessons about the not-so-scientific ways in which personal experience rather than market information can determine optimism, pessimism, and access to credit.
Gary Oldman's first film as director in 20 years, and only his second ever, is a biopic of the pioneering 19th-century photographer Eadweard Muybridge, focusing on the affair between his wife, Flora, and Harry Larkyns, the theatre critic he kills. No casting confirmed, but Oldman had been chasing Ralph Fiennes and Benedict Cumberbatch. The man himself will play Muybridge's prosecutor.
The Bellarine Peninsula, located Southwest of Melbourne, Victoria, has been a hotspot for timeless beaches and historic towns like Queenscliff and Portarlington.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 许勤率团赴香港举行招商引资活动
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

The remains of the monarch -- depicted by William Shakespeare as a monstrous hunchback and often viewed as one of English history's greatest villains -- will now be solemnly reburied in the local cathedral.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

['p?:ts]
“…brought his dog.”
公牛队当家球星罗斯的这两张照片就跟在照镜子一样,可能是因为照片中的罗斯还处于2006年的高中时代,也不过是六年前。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

中国互联网金融行业继续保持快速增长的节奏。作为国内最大的个人对个人(P2P)网贷平台,陆金所(Lufax)正在寻求10亿美元的新融资,这将使其估值达到150亿至200亿美元。
Ultimately I expect these new leaders to start selecting from a broader pool of candidates and appoint direct reports from more varied backgrounds, defying those who use current imbalances to extrapolate gloomily that leadership parity between men and women is still decades off.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: 机构预计明年降价楼盘或将增多
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Recently, a recruitment website issued the Investigation Report of Employability of 2016 Graduates. The report notes that starting salaries for 2016 graduates are 4765 Yuan, nearly 30% graduates to enter the Internet industry which provide the highest average salary.
New Year's greetings and best wishes!

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

感谢和凯尔特人的选秀权交换,他们没有理由摆烂。他们或许会从参选球员中选到一个最佳安慰奖以推动球队前行。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

单词neglect 联想记忆:
让它具有一定的危险性,因为这也会让你的“华生”兴趣盎然。
['?nim'pl?im?nt]

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

数据显示,在欧洲外的最受游客欢迎20大目的地中,游客的消费主要用于购物,而非就餐。尽管其中很多是世界著名的美食之都。
该项目在毕业3年后的职业晋升方面排名第二。Tiemba项目的毕业生数量迄今只有约250人,使他们成为一个精英团体。
The thing about the Mavericks is that this is not at all how Dirk should go out. That team has been so solid his entire career. To have a busted season now is painful. Maybe he ought to have joined Kobe, KG, and Big Fundamental last summer.
单词释义:

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

5. Broadcaster
OUTDOOR SPACE: The house is on a fifth of an acre, landscaped by the New York firm Landgarden. The Japanese-style gardens in front make use of native plants. There’s also a back patio and yard, with a second Japanese garden.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 城六区土地供应量占总量18%
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

报告显示,今年11月11日至15日五天期间,涉及电商平台、电商企业、物流公司、第三方支付机构、消费者等主体的失信案例数量同比增加57.49%。
China will continue to improve market environment and tap consumption potential while developing complementary cross-border industrial and value chain with countries along the Belt and Road Initiative in the next five years, according to Gao.
出演《美国队长3:英雄决裂》的斯嘉丽-约翰逊排名第三,收入为2500万美元,比去年下降了近30%。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 六大基建新任务利好建材业
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About this collection

"We will set the exact date and location for our operation in consideration of weather conditions, but it will not be publicised," said Park Sang-Hak, a former defector who has led a series of balloon launches
Next year will be the 60th anniversary of the beloved talking bear. And to mark the occasion, Paul King, who directed 2014’s critical and commercial smash, simply titled Paddington, is back for this sequel. In a time where even children’s entertainments are suffused with darkness and violence, this quiet celebration of the everyday English is needed more than ever. The plot of this film? Well, not much really: following the events of the last film, Paddington is quite comfortably installed with the Brown family of Windsor Gardens. He wants to buy a pop-up book for his aunt from a local bookseller, but finding himself a few quid short he puts on his wellies and duffel coat and finds employment in various odd jobs – only to have the book stolen from the shop! A (not so serious) mystery begins. Expect many more jokes about Paddington’s love of marmalade. Released in the UK November 10, November 23 in Germany and November 30 in Cambodia and Malaysia. (Credit: StudioCanal)

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